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Introducing the big biology blog!

This piece reframes the ocean not as a passive backdrop for climate change, but as a reservoir of biological ingenuity that could solve human crises. Big Biology argues that the most sophisticated medical and engineering breakthroughs of the next century may not come from high-tech labs, but from the "unsung heroes" of the deep: sponges, corals, and sea stars. For a reader short on time, the takeaway is stark: we are risking the loss of a library of life before we have even read the books.

The Biology of the Simple

The article opens by dismantling the assumption that complexity equals capability. It highlights Dr. Drew Harvell's work, which reveals that sea sponges—creatures without organs or true tissue—possess a biological sophistication that rivals human engineering. The piece notes that these organisms are "creatures of current," utilizing microscopic cells to filter water with a precision that outperforms many man-made systems. But their true value lies in their chemistry. Harvell is quoted explaining that "tropical sponges had the highest hit rate on the planet for the discovery of new anti-cancer chemicals." This is not merely a biological curiosity; it is a direct link between biodiversity and human survival.

Introducing the big biology blog!

The commentary here is compelling because it shifts the metric of value from economic extraction to biological utility. The article emphasizes that these creatures produce "phenomenal sophistication and complexity of the compounds" that can disrupt cell division or control inflammation. The argument suggests that protecting these habitats is an investment in future medicine, not just an environmental luxury. Critics might argue that the timeline for translating these compounds into viable drugs is often decades long, making the urgency of conservation feel abstract to policymakers. However, the piece counters this by noting that once a species is extinct, that potential is gone forever.

"The most valuable resource on our planet is not oil or metal, it's our living resources and the web of life that links them together."

Engineering and Adaptation

Moving beyond chemistry, the coverage explores the structural genius of corals and the tactical flexibility of sea stars. The article details how coral reefs are not just passive rock formations but active "calcifying castles" built through a symbiotic partnership with algae. This relationship is described as a "double win," where the algae not only provide energy but also optimize the internal pH to accelerate skeleton building. The piece goes further, noting that the reef's architecture acts as a "hall of mirrors," reflecting light to boost photosynthesis speed. This reframes the reef as a masterclass in materials science, one that human engineers are only beginning to understand.

Similarly, the sea star is presented not as a slow-moving oddity, but as a predator with "mutable collagenous tissue"—essentially "sticky skin" under neural control. This allows them to stiffen their bodies to pry open clams or soften to squeeze through cracks. The article highlights the sea star's ability to "de-differentiate" cells, comparing them to the comic book character Deadpool, capable of regenerating lost limbs. This cellular plasticity offers profound insights for regenerative medicine. The narrative effectively uses these examples to show that evolution has already solved problems that human science is still struggling to crack.

The Fragility of Superpowers

Despite the celebration of these biological marvels, the piece delivers a sobering reality check: these superpowers have a kryptonite. The article argues that the very symbiotic relationships that make these creatures successful are their greatest vulnerability in a warming ocean. Harvell is quoted warning that when temperatures rise, these delicate partnerships break down, leaving sponges without detoxifying microbes and corals without their energy source. The text notes that "sea star wasting disease" has already devastated over 20 species, with research showing the disease's impact intensifies at higher temperatures.

The commentary here is critical because it refuses to let the reader off the hook with a simple "save the whales" sentiment. Instead, it connects the dots between global heating and the collapse of specific biological mechanisms. The piece suggests that as marine heatwaves become more frequent, the "superpowers" of these invertebrates will become increasingly vulnerable. A counterargument worth considering is whether these creatures possess enough adaptive capacity to evolve quickly enough to survive rapid climate shifts. Harvell herself hints at this uncertainty, stating, "I haven't thought of any new superpowers that have emerged in the last 200 million years," yet she remains hopeful that under stress, "we could expect some pretty crazy stuff to pop up." This tension between extinction risk and evolutionary resilience is the central drama of the piece.

Bottom Line

The strongest element of this coverage is its ability to translate complex marine biology into a narrative of human dependency, making the abstract concept of biodiversity loss feel immediate and personal. Its biggest vulnerability is the inherent difficulty in conveying the scale of the threat without inducing paralysis; the piece walks a fine line between awe and alarm. Readers should watch for how the scientific community leverages these specific biological discoveries to drive policy changes, as the argument that "protecting the ocean is inseparable from human health" gains traction in the face of accelerating climate data.

Sources

Introducing the big biology blog!

Welcome to the inaugural Big Biology Blog! I’m Clayton Glasgow, an avid Big Biology listener, and I now have the wonderful privilege of writing blog posts about Big Biology episodes. I earned my bachelor’s degree in Environmental Science at the University of Notre Dame, where I am now pursuing my Master’s of Education through the Alliance for Catholic Education Teaching Fellows program. As part of this program, I currently serve as a high school biology and environmental science teacher in Cleveland, Ohio. I am passionate about science education, and I am excited to become more involved with science communication.

I’ll be writing short blogs that capture some of the major themes and insights from many Big Biology episodes and sharing them here on Substack. Please feel free to leave comments with any questions, critiques, or suggestions you might have, both about the blog and the episode itself. Listener and reader perspectives help us think more critically about the science we share and enrich the Big Biology community for all involved–we encourage you to share your thoughts. If you enjoy this blog, please share it with anyone else you think might also be interested. Now onto the first blog post about our recent episode Not all heroes have spines with Dr. Drew Harvell!

Unsung heroes: Marine invertebrate superpowers in a changing ocean.

By Clayton Glasgow

I’m a high school biology teacher, and I recently asked my students the age-old question, “If you could have any superpower, which would you choose?” Many answered with the classics you might expect: flight, invisibility, teleportation, telekinesis, x-ray vision, or super speed. One creative student said she wanted the power to make anyone she didn’t want to hear talk be silent (she promised it wasn’t directed at me). All of my students scoffed at my desire to be fluent in all forms of communication, although I still think it would be an amazing (albeit, slightly nerdy) superpower.

Dr. Drew Harvell, a recent featured guest on Big Biology, is an expert on superpowers, but not on the superpowers of comics, movies or students’ imaginations. She studies the real-life superpowers of some of the ocean’s most important and fantastic creatures. Her new book, The Ocean’s Menagerie: How Earth's Strangest Creatures Reshape the Rules of Life, is an exploration and celebration of some of the ocean’s unsung heroes—invertebrates—and how marine invertebrate superpowers might inspire new breakthroughs in medicine and ...