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BioByte 136: Scaling Laws for pLMs, DeepSomatic and CASTLE for Oncological Variant Calling, Ballistic Microscopy for Cellular Imaging, Neural Circuitry for Encoding of Inferred Contours

Pranay Satya · ·Oct 16, 2025 · 16 min read · Law & Rights

The Myth of the Toddler Testosterone Surge

Cara Goodwin · Parenting Translator ·Oct 16, 2025 · 10 min read · Science

Shift Change at the Wheel Reinvention Factory

Hamilton Nolan · ·Oct 16, 2025 · 10 min read · Culture

More on US Pedestrian Deaths

Brian Potter · Construction Physics ·Oct 16, 2025 · 17 min read · Housing & Cities

On Peter Howitt's Other Work

Brian Albrecht · Economic Forces ·Oct 16, 2025 · 14 min read · Economics

Was consciousness invented at the Bronze Age collapse?

Tove K · ·Oct 16, 2025 · 21 min read · Philosophy

The case for debating the other side

Karim Zidan · ·Oct 16, 2025 · 11 min read · Culture

The main way I've seen people turn ideologically crazy

Andy Masley · ·Oct 15, 2025 · 11 min read · Culture

A Practical Roadmap to AI Fluency for Hardware Designers

Vikram Sekar · Vik's Newsletter ·Oct 15, 2025 · 11 min read · AI & Tech

The art of protein design with AI

Various · Works in Progress ·Oct 15, 2025 · 48 min read · AI & Tech

Each of Us Imperfect Comrades

Margaret Killjoy · Birds Before the Storm ·Oct 15, 2025 · 12 min read · Political Strategy

An Interview With Mohamed Awad About Chiplets

Various · Chipstrat ·Oct 15, 2025 · 22 min read · AI & Tech

What Are the Best "Bad" Movies? A Statistical Analysis

Daniel Parris · ·Oct 15, 2025 · 12 min read · Culture

Was Famed Author Peter Matthiessen a Spy or an Informant?

Lee Fang · ·Oct 15, 2025 · 12 min read · Writing & Craft

Driverless taxis are coming to London's streets in the Spring

Michael Macleod · London Centric ·Oct 15, 2025 · 12 min read · Culture

How a Hospital Librarian Spends Their Days

Anne Helen Petersen · ·Oct 15, 2025 · 12 min read · Public Health

Secular Messianism

Anarchierkegaard · Kierkegaardian Reflections ·Oct 15, 2025 · 12 min read · Philosophy

New Research: Ben Greenberg

Gary Hustwit · Gary Hustwit's Films ·Oct 14, 2025 · 22 min read · Culture

The Mystery of Diane Ravitch

Natalie Wexler · Natalie Wexler ·Oct 14, 2025 · 10 min read · Culture

Learned helplessness is hurting the security industry

Ross Haleliuk · Venture in Security ·Oct 14, 2025 · 12 min read · AI & Tech

A Cross Between Dubravka Ugresic & Georgi Gospodinov

Chad W. Post · Three Percent ·Oct 14, 2025 · 12 min read · Writing & Craft

Good news

Naomi Kanakia · ·Oct 14, 2025 · 11 min read · Culture

The Battle for the Soul of American Higher Education

Roger Pielke Jr. · The Honest Broker ·Oct 14, 2025 · 10 min read · Culture

The Anatomy of the Least Squares Method, Part One

Tivadar Danka · The Palindrome ·Oct 13, 2025 · 14 min read · Economics

Choosing a GGUF Model: K-Quants, I-Quants, and Legacy Formats

Various · The Kaitchup ·Oct 13, 2025 · 10 min read · AI & Tech

And the 2025 Economics Nobel Goes to...

Brian Albrecht · Economic Forces ·Oct 13, 2025 · 12 min read · Economics

Import AI 431: Technological Optimism and Appropriate Fear

Jack Clark · Import AI ·Oct 13, 2025 · 23 min read · AI & Tech

The Cost of Standardization

Adrian Neibauer · Notes on the State of Education ·Oct 13, 2025 · 17 min read · Culture

Life Under Martial Law

Various · Animation Obsessive ·Oct 12, 2025 · 11 min read · Culture

Monopoly Round-Up: Will the Trade War Pop the AI Bubble?

Matt Stoller · ·Oct 12, 2025 · 10 min read · AI & Tech
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